Coming closer to FDA reform

FDA Reform: Déjà Vu Encore

The Food and Drug Administration (FDA) creates the climate for the development of new drugs and clinical research. A 30 year struggle to bring drugs to the market more rapidly culminated in the 1992 Prescription Drug User Fee Act (PDUFA). While drug review times have shortened, concerns about drug safety possibly associated with more rapid reviews have led FDA and Congress to tighten safety req...

FDA Reform and the European Medicines Evaluation Agency

Decoding the role of chromatin architecture in development: coming closer to the end of the tunnel

Form and function in biology are intimately related aspects that are often difficult to untangle. While the structural aspects of chromatin organization were apparent from early cytological observations long before the molecular details of chromatin functions were deciphered, the extent to which genome architecture may impact its output remains unclear. A major roadblock to resolve this issue i...

Synthetic talc advances: Coming closer to nature, added value, and industrial requirements

a r t i c l e i n f o Over the past 2 years, the synthetic process of talc particles has evolved considerably, leading to an inexpensive, convenient, and rapid process that is compatible with industrial requirements. In addition to facilitate the synthetic talc preparation, the evolution of the synthesis process has led to an improved crystallographic arrangement of the talc particles in both t...

Medicare's Future: Policy Ideas and the Coming Reform Debate.